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Role of Histopathologist in Liver Transplantation
#MMPMID28299022
Geramizadeh B
; Malek-Hosseini SA
Int J Organ Transplant Med
2017[]; 8
(1
): 1-6
PMID28299022
show ga
A successful liver transplantation team consists of several specialists to work
closely together. The histopathologist (anatomical pathologist) is one of the key
players in this multidisciplinary team. This role starts with the
pre-transplantation evaluation of the recipient's liver by diagnosis or
confirming the underlying liver disease and continues with the evaluation of the
explanted recipient's liver for any further information about the underlying
liver disease including malignancies such as hepatocellular carcinoma,
cholangiocarcinoma, or any other incidental findings. The evaluation of the new
donor liver begins with determining the suitability of the donor liver for
transplantation during or before the operation and continues throughout the
entire post-transplantation period by evaluating not only the allograft diseases
but also evaluating other tissues for infections, malignancies, etc. It is worthy
to note that in many of the above-mentioned situations, histopathology is the
gold-standard diagnostic test. In this review, we present on various tasks of a
histopathologist according to the current literature and our own experience in
the largest liver transplantation center in Iran.