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Rhinocerebral mucormycosis: a retrospective study
#MMPMID25621242
Kolekar JS
Indian J Otolaryngol Head Neck Surg
2015[Mar]; 67
(1
): 93-6
PMID25621242
show ga
Mucormycosis is an acute often fatal infection caused by fungi of family
mucoracea (Kauffman and Malani Curr Infect Dis Rep 9(6):435-440). The principal
pathogens in this family are rhizopus, mucor and absidia species. Mucoracea are
found in soil, decaying vegetation and other organic matter. Mucormycosis is a
polymorphic disease with diverse clinical manifestation. It is divided into
rhinocerebral, pulmonary, cutaneous, cardiac, gastrointestinal and disseminated.
Rhinocerebral mucormycosis the most commonest manifestation of mucormycosis is
usually a fatal fulminant infection. Rhinocerebral mucormycosis can be further
divided into rhino-maxillary and rhino-orbito-cerebral. The disease commonly
occur in diabetics who have ketoacidosis but is also seen in severely debilitated
or immunosuppressed patients. It has also been reported from otherwise normal
individuals. Early diagnosis and treatment is mandatory for a successful
management of this infection.