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2017 ; 6
(4
): 161-168
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Rhabdomyolysis with different etiologies in childhood
#MMPMID29184760
Alaygut D
; Torun Bayram M
; Kasap B
; Soylu A
; Türkmen M
; Kavukcu S
World J Clin Pediatr
2017[Nov]; 6
(4
): 161-168
PMID29184760
show ga
AIM: To investigate different etiologies and management of the rhabdomyolysis in
children. METHODS: Eight pediatric rhabdomyolysis cases who applied to the Dokuz
Eylul University Faculty of Medicine Department of Pediatric Nephrology with
different etiologies between January 2004 and January 2012 were evaluated in
terms of age, gender, admission symptoms, physical examination findings, factors
provoking rhabdomyolysis, number of rhabdomyolysis attacks, laboratory results,
family history and the final diagnosis received after the treatment. RESULTS:
Average diagnosis ages of eight cases were 129 (24-192) ± 75.5 mo and five of
them were girls. All of them had applied with the complaint of muscle pain, calf
pain, and dark color urination. Infection (pneumonia) and excessive physical
activity were the most important provocative factors and excessive licorice
consumption was observed in one case. In 5 cases, acute kidney injury was
determined and two cases needed hemodialysis. As a result of the further
examinations; the cases had received diagnoses of rhabdomyolysis associated with
mycoplasma pneumoniae, sepsis associated rhabdomyolysis, licorice-induced
hypokalemic rhabdomyolysis, carnitine palmitoyltransferase II deficiency, very
long-chain acyl-CoA dehydrogenase deficiency, congenital muscular dystrophy and
idiopathic paroxysmal rhabdomyolysis (Meyer-Betz syndrome). CONCLUSION: It is
important to distinguish the sporadic and recurrent rhabdomyolysis cases from
each other. Recurrent rhabdomyolysis cases should follow up more regardful and
attentive.