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2017 ; 13
(ä): 471-495
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Reward Processing, Neuroeconomics, and Psychopathology
#MMPMID28301764
Zald DH
; Treadway MT
Annu Rev Clin Psychol
2017[May]; 13
(ä): 471-495
PMID28301764
show ga
Abnormal reward processing is a prominent transdiagnostic feature of
psychopathology. The present review provides a framework for considering the
different aspects of reward processing and their assessment, and highlights
recent insights from the field of neuroeconomics that may aid in understanding
these processes. Although altered reward processing in psychopathology has often
been treated as a general hypo- or hyperresponsivity to reward, increasing data
indicate that a comprehensive understanding of reward dysfunction requires
characterization within more specific reward-processing domains, including
subjective valuation, discounting, hedonics, reward anticipation and
facilitation, and reinforcement learning. As such, more nuanced models of the
nature of these abnormalities are needed. We describe several processing
abnormalities capable of producing the types of selective alterations in
reward-related behavior observed in different forms of psychopathology, including
(mal)adaptive scaling and anchoring, dysfunctional weighting of reward and cost
variables, competition between valuation systems, and reward prediction error
signaling.