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10.4103/0253-7613.157109 http://scihub22266oqcxt.onion/10.4103/0253-7613.157109 C4450548!4450548 !26069360     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26069360 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Indian+J+Pharmacol 2015 ; 47 (3 ): 248-55 Nephropedia Template TP {{tp|p=26069360 |t=2015. Reversing resistance: The next generation antibacterials |pdf=|usr=}}{{26069360 }} gab.com Text Reversing resistance: The next generation antibacterials JO: Indian J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26069360 #FOAvip Irrational antibiotic usage has led to vast spread resistance to available antibiotics, but we refuse to slide back to "preantibiotic era." The threat is serious with the "Enterococcus, Staphylococcous, Klebsiella, Acinetobacter, Pseudomonas and Enterobacter" organisms causing nosocomial infections that are difficult to treat because of the production of extended spectrum ?-lactamases, carbapenamases and metallo-?-lactamases. Facing us is a situation where soon multidrug resistance would have spread across the globe with no antibiotics to withstand it. The infectious disease society of America and Food and Drug Administration have taken initiatives like the 10 × '20 where they plan to develop 10 new antibiotics by the year 2020. Existing classes of antibiotics against resistant bacteria include the carbapenems, oxazolidinones, glycopeptides, monobactams, streptogramins and daptomycin. Newer drugs in existing classes of antibiotics such as cephalosporins, aminoglycosides, tetracyclines, glycopeptides and ?-lactamase inhibitors continue to get synthesized. The situation demands newer targets against bacterial machinery. Some of them include the peptidoglycantransferase, outer membrane protein of Pseudomonas, tRNA synthase, fatty acid synthase and mycobacterial ATP synthase. To curb the irrational and excessive usage of presently available antibiotics should be a priority if they are still to be kept in usage for the future. Twit Text FOAVip Reversing resistance: The next generation antibacterials ????Indian J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=26069360 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26069360 #FOAvip English Wikipedia <ref>{{Cite pmid|26069360 }}</ref> Reversing resistance: The next generation antibacterials #MMPMID26069360 Shah NJ Indian J Pharmacol 2015[May]; 47 (3 ): 248-55 PMID26069360 show ga Irrational antibiotic usage has led to vast spread resistance to available antibiotics, but we refuse to slide back to "preantibiotic era." The threat is serious with the "Enterococcus, Staphylococcous, Klebsiella, Acinetobacter, Pseudomonas and Enterobacter" organisms causing nosocomial infections that are difficult to treat because of the production of extended spectrum ?-lactamases, carbapenamases and metallo-?-lactamases. Facing us is a situation where soon multidrug resistance would have spread across the globe with no antibiotics to withstand it. The infectious disease society of America and Food and Drug Administration have taken initiatives like the 10 × '20 where they plan to develop 10 new antibiotics by the year 2020. Existing classes of antibiotics against resistant bacteria include the carbapenems, oxazolidinones, glycopeptides, monobactams, streptogramins and daptomycin. Newer drugs in existing classes of antibiotics such as cephalosporins, aminoglycosides, tetracyclines, glycopeptides and ?-lactamase inhibitors continue to get synthesized. The situation demands newer targets against bacterial machinery. Some of them include the peptidoglycantransferase, outer membrane protein of Pseudomonas, tRNA synthase, fatty acid synthase and mycobacterial ATP synthase. To curb the irrational and excessive usage of presently available antibiotics should be a priority if they are still to be kept in usage for the future. |Anti-Bacterial Agents/*pharmacology/*supply & distribution [MESH] |Drug Resistance, Multiple, Bacterial/*drug effects [MESH] |Drug and Narcotic Control/legislation & jurisprudence [MESH] |Drugs, Investigational/*pharmacology/*supply & distribution [MESH] |Humans [MESH] |Molecular Targeted Therapy/*methods [MESH] |United States [MESH]Reversing resistance: The next generation antibacterials (epmc).pdf DeepDyve Pubget Overpricing