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2016 ; 3
(ä): 43-46
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Retinopathy in lupus transitioned to Kikuchi-Fujimoto disease
#MMPMID29503907
Rue KS
; Rodger DC
; Rao NA
Am J Ophthalmol Case Rep
2016[Oct]; 3
(ä): 43-46
PMID29503907
show ga
PURPOSE: We present a patient with systemic lupus erythematosus with significant
vaso-occlusive retinal findings mimicking antiphospholipid antibody syndrome, who
developed Kikuchi-Fujimoto disease. OBSERVATIONS: Our patient was initially
diagnosed with systemic lupus erythematosus with antiphospholipid antibody
syndrome given consistent serologic markers and profound retinal vascular
ischemia. However, on subsequent follow up, she presented with fever and
lymphadenopathy and underwent lymph node biopsy, which declared histologic
findings of Kikuchi-Fujimoto disease. Repeat markers for antiphospholipid
antibody syndrome were negative and she was taken off lifelong anticoagulation.
CONCLUSIONS AND IMPORTANCE: Systemic lupus erythematosus and Kikuchi-Fujimoto
disease may have many similar features and even biomarkers, and given the
potential overlap of presentation, clinicians must carefully distinguish between
these diseases to prevent unnecessary treatment.