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10.18632/oncotarget.22527 http://scihub22266oqcxt.onion/10.18632/oncotarget.22527 C5844762!5844762 !29552326     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29552326 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Oncotarget 2018 ; 9 (15 ): 12471-12478 Nephropedia Template TP {{tp|p=29552326 |t=2018. Research progress on the forkhead box C1 |pdf=|usr=}}{{29552326 }} gab.com Text Research progress on the forkhead box C1 JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29552326 #FOAvip FOXC1 is a vital member of FOX families which play important roles in biological processes including proliferation, differentiation, apoptosis, migration, invasion, metabolism, and longevity. Here we are focusing on roles of FOXC1 and their mechanisms in cancers. FOXC1 promoted progress of many cancers, such as breast cancer (especially basal-like breast cancer), hepatocellular carcinoma, gastric cancer and so on. FOXC1 was also found to be associated with drug resistance of cancers. FOXC1 promoted metastasis of cancers by increasing expression of MMP7, NEDD9 and Snail. Proliferation and invasion of cancers were increased by FOXC1 by mediating NF-?B, MST1R and KLF4 expression. FOXC1 was associated with development by regulating expression of FGF19 and MSX1. Recently, FOXC1 was found to be required for niche of stem cells or development of stem cells by mediating expression of Gli2, CXCL12, SCF, NFATC1, BMP and Myh7. Overall, FOXC1 exerts its functions by many mechanisms and may be used as a potential biomarker for diseases. Twit Text FOAVip Research progress on the forkhead box C1 ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29552326 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29552326 #FOAvip English Wikipedia <ref>{{Cite pmid|29552326 }}</ref> Research progress on the forkhead box C1 #MMPMID29552326 Wang J ; Li W ; Zheng X ; Pang X ; Du G Oncotarget 2018[Feb]; 9 (15 ): 12471-12478 PMID29552326 show ga FOXC1 is a vital member of FOX families which play important roles in biological processes including proliferation, differentiation, apoptosis, migration, invasion, metabolism, and longevity. Here we are focusing on roles of FOXC1 and their mechanisms in cancers. FOXC1 promoted progress of many cancers, such as breast cancer (especially basal-like breast cancer), hepatocellular carcinoma, gastric cancer and so on. FOXC1 was also found to be associated with drug resistance of cancers. FOXC1 promoted metastasis of cancers by increasing expression of MMP7, NEDD9 and Snail. Proliferation and invasion of cancers were increased by FOXC1 by mediating NF-?B, MST1R and KLF4 expression. FOXC1 was associated with development by regulating expression of FGF19 and MSX1. Recently, FOXC1 was found to be required for niche of stem cells or development of stem cells by mediating expression of Gli2, CXCL12, SCF, NFATC1, BMP and Myh7. Overall, FOXC1 exerts its functions by many mechanisms and may be used as a potential biomarker for diseases. äResearch progress on the forkhead box C1 (epmc).pdf DeepDyve Pubget Overpricing