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10.1016/j.bmcl.2016.03.103 http://scihub22266oqcxt.onion/10.1016/j.bmcl.2016.03.103 C4853260!4853260 !27080183     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27080183 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27080183 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Bioorg+Med+Chem+Lett 2016 ; 26 (11 ): 2569-76 Nephropedia Template TP {{tp|p=27080183 |t=2016. Repurposing strategies for tropical disease drug discovery |pdf=|usr=}}{{27080183 }} gab.com Text Repurposing strategies for tropical disease drug discovery JO: Bioorg Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=27080183 #FOAvip Neglected tropical diseases (NTDs) and other diseases of the developing world, such as malaria, attract research investments that are disproportionately low compared to their impact on human health worldwide. Therefore, pragmatic methods for launching new drug discovery programs have emerged that repurpose existing chemical matter as new drugs or new starting points for optimization. In this Digest we describe applications of different repurposing approaches for NTDs, and provide a means by which these approaches may be differentiated from each other. These include drug repurposing, target repurposing, target class repurposing, and lead repurposing. Twit Text FOAVip Repurposing strategies for tropical disease drug discovery ????Bioorg Med Chem Lett http://www.kidney.de/pget.php?&tw=1&pmid=27080183 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27080183 #FOAvip English Wikipedia <ref>{{Cite pmid|27080183 }}</ref> Repurposing strategies for tropical disease drug discovery #MMPMID27080183 Klug DM ; Gelb MH ; Pollastri MP Bioorg Med Chem Lett 2016[Jun]; 26 (11 ): 2569-76 PMID27080183 show ga Neglected tropical diseases (NTDs) and other diseases of the developing world, such as malaria, attract research investments that are disproportionately low compared to their impact on human health worldwide. Therefore, pragmatic methods for launching new drug discovery programs have emerged that repurpose existing chemical matter as new drugs or new starting points for optimization. In this Digest we describe applications of different repurposing approaches for NTDs, and provide a means by which these approaches may be differentiated from each other. These include drug repurposing, target repurposing, target class repurposing, and lead repurposing. |*Drug Discovery [MESH] |Humans [MESH] |Molecular Structure [MESH]Repurposing strategies for tropical disease drug discovery (epmc).pdf DeepDyve Pubget Overpricing