Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26998249
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26998249
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 F1000Res
2016 ; 5
(ä): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Renal protection in cardiovascular surgery
#MMPMID26998249
Di Tomasso N
; Monaco F
; Landoni G
F1000Res
2016[]; 5
(ä): ä PMID26998249
show ga
Acute kidney injury (AKI) is one of the most relevant complications after major
surgery and is a predictor of mortality. In Western countries, patients at risk
of developing AKI are mainly those undergoing cardiovascular surgical procedures.
In this category of patients, AKI depends on a multifactorial etiology, including
low ejection fraction, use of contrast media, hemodynamic instability,
cardiopulmonary bypass, and bleeding. Despite a growing body of literature, the
treatment of renal failure remains mainly supportive (e.g. hemodynamic stability,
fluid management, and avoidance of further damage); therefore, the management of
patients at risk of AKI should aim at prevention of renal damage. Thus, the
present narrative review analyzes the pathophysiology underlying AKI
(specifically in high-risk patients), the preoperative risk factors that
predispose to renal damage, early biomarkers related to AKI, and the strategies
employed for perioperative renal protection. The most recent scientific evidence
has been considered, and whenever conflicting data were encountered possible
suggestions are provided.