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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Curr+Probl+Cancer
2017 ; 41
(2
): 100-110
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Renal complications of immune checkpoint blockade
#MMPMID28189263
Murakami N
; Motwani S
; Riella LV
Curr Probl Cancer
2017[Mar]; 41
(2
): 100-110
PMID28189263
show ga
Immune checkpoint inhibitors have been approved for a variety of cancer species.
Renal complications in use of these agents are not very common compared with
other immune-related adverse events (irAE). However, it is crucial for physicians
to recognize and manage renal manifestations of irAE. In this review, we will
summarize the up-to-date knowledge of the clinical presentation, pathologic
features, and management of renal irAE. In addition, we will discuss the safety
of immune checkpoint inhibitors in patients with chronic kidney disease as well
as in kidney transplant recipients.
|Animals
[MESH]
|Antibodies, Monoclonal/*adverse effects
[MESH]
|Antineoplastic Agents/*adverse effects
[MESH]
|Humans
[MESH]
|Immunomodulation/*drug effects
[MESH]
|Kidney Diseases/*chemically induced/*immunology/prevention & control
[MESH]