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10.1155/2016/8342625 http://scihub22266oqcxt.onion/10.1155/2016/8342625 C4884584!4884584 !27293448     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27293448 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Stem+Cells+Int 2016 ; 2016 (ä): 8342625 Nephropedia Template TP {{tp|p=27293448 |t=2016. Renal Cancer Stem Cells: Characterization and Targeted Therapies |pdf=|usr=}}{{27293448 }} gab.com Text Renal Cancer Stem Cells: Characterization and Targeted Therapies JO: Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=27293448 #FOAvip Renal cell carcinoma (RCC) is a major neoplasm with high incidence in western countries. Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells, and cancer stem cells (CSCs). CSCs possess two main properties: self-renewal and proliferation. Additionally, they can generate new tumors once transplanted into immunodeficient mice. Several approaches have been described to identify them, through the expression of cell markers, functional assays, or a combination of both. As CSCs are involved in the resistance mechanisms to radio- and chemotherapies, several new strategies have been proposed to directly target CSCs in RCC. One approach drives CSCs to differentiate into cancer cells sensitive to conventional treatments, while the other proposes to eradicate them selectively. A series of innovative therapies aiming at eliminating CSCs have been designed to treat other types of cancer and have not been experimented with on RCC yet, but they reveal themselves to be promising. In conclusion, CSCs are an important player in carcinogenesis and represent a valid target for therapy in RCC patients. Twit Text FOAVip Renal Cancer Stem Cells: Characterization and Targeted Therapies ????Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=27293448 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27293448 #FOAvip English Wikipedia <ref>{{Cite pmid|27293448 }}</ref> Renal Cancer Stem Cells: Characterization and Targeted Therapies #MMPMID27293448 Peired AJ ; Sisti A ; Romagnani P Stem Cells Int 2016[]; 2016 (ä): 8342625 PMID27293448 show ga Renal cell carcinoma (RCC) is a major neoplasm with high incidence in western countries. Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells, and cancer stem cells (CSCs). CSCs possess two main properties: self-renewal and proliferation. Additionally, they can generate new tumors once transplanted into immunodeficient mice. Several approaches have been described to identify them, through the expression of cell markers, functional assays, or a combination of both. As CSCs are involved in the resistance mechanisms to radio- and chemotherapies, several new strategies have been proposed to directly target CSCs in RCC. One approach drives CSCs to differentiate into cancer cells sensitive to conventional treatments, while the other proposes to eradicate them selectively. A series of innovative therapies aiming at eliminating CSCs have been designed to treat other types of cancer and have not been experimented with on RCC yet, but they reveal themselves to be promising. In conclusion, CSCs are an important player in carcinogenesis and represent a valid target for therapy in RCC patients. äRenal Cancer Stem Cells: Characterization and Targeted Therapies (epmc).pdf DeepDyve Pubget Overpricing