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2018 ; 8
(ä): 98
Nephropedia Template TP
Talagrand-Reboul E
; Boyer PH
; Bergström S
; Vial L
; Boulanger N
Front Cell Infect Microbiol
2018[]; 8
(ä): 98
PMID29670860
show ga
Relapsing fever still remains a neglected disease and little is known on its
reservoir, tick vector and physiopathology in the vertebrate host. The disease
occurs in temperate as well as tropical countries. Relapsing fever borreliae are
spirochaetes, members of the Borreliaceae family which also contain Lyme disease
spirochaetes. They are mainly transmitted by Ornithodoros soft ticks, but some
species are vectored by ixodid ticks. Traditionally a Borrelia species is
associated with a specific vector in a particular geographical area. However, new
species are regularly described, and taxonomical uncertainties deserve further
investigations to better understand Borrelia vector/host adaptation. The medical
importance of Borrelia miyamotoi, transmitted by Ixodes spp., has recently
spawned new interest in this bacterial group. In this review, recent data on
tick-host-pathogen interactions for tick-borne relapsing fevers is presented,
with special focus on B. miyamotoi.