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Relapse of nephrotic syndrome triggered by Kawasaki disease
#MMPMID29143203
Maeda R
; Kawasaki Y
; Suzuki S
; Ohara S
; Kazuhide S
; Hosoya M
CEN Case Rep
2018[May]; 7
(1
): 13-16
PMID29143203
show ga
Minor infections, allergies, insect bites, and bee stings are commonly reported
causes of nephrotic syndrome (NS). Herein, we report, to the best of our
knowledge, the first case of NS relapse due to Kawasaki disease (KD). An
8-year-old boy presented with high fever of 4-day duration. He had developed
steroid-dependent NS at the age of 4 years and remained in remission after
steroid and mizonbin therapy. Renal biopsy, performed at the age of four, showed
minimal change (MC) disease. Upon examination, the patient fulfilled 5 of 6
criteria for KD under the Japanese diagnostic guidelines, with positive
proteinuria. He was diagnosed with NS relapse caused by KD. Proteinuria resolved
after treatment with intravenous immunoglobulin and cyclosporine A. We present
the case of an 8-year-old boy, whose NS relapsed due to KD. To the best of our
knowledge, this is the first case report. It is necessary to recognize that KD
can trigger relapse of MCNS.