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10.1038/nri.2015.1 http://scihub22266oqcxt.onion/10.1038/nri.2015.1 C5113825!5113825 !26688349     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26688349 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Nat+Rev+Immunol 2016 ; 16 (2 ): 90-101 Nephropedia Template TP {{tp|p=26688349 |t=2016. Regulatory T cell memory |pdf=|usr=}}{{26688349 }} gab.com Text Regulatory T cell memory JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26688349 #FOAvip Memory for antigen is a defining feature of adaptive immunity. Antigen-specific lymphocyte populations show an increase in number and function after antigen encounter and more rapidly re-expand upon subsequent antigen exposure. Studies of immune memory have primarily focused on effector B cells and T cells with microbial specificity, using prime-challenge models of infection. However, recent work has also identified persistently expanded populations of antigen-specific regulatory T cells that protect against aberrant immune responses. In this Review, we consider the parallels between memory effector T cells and memory regulatory T cells, along with the functional implications of regulatory memory in autoimmunity, antimicrobial host defence and maternal-fetal tolerance. In addition, we discuss emerging evidence for regulatory T cell memory in humans and key unanswered questions in this rapidly evolving field. Twit Text FOAVip Regulatory T cell memory ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26688349 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26688349 #FOAvip English Wikipedia <ref>{{Cite pmid|26688349 }}</ref> Regulatory T cell memory #MMPMID26688349 Rosenblum MD ; Way SS ; Abbas AK Nat Rev Immunol 2016[Feb]; 16 (2 ): 90-101 PMID26688349 show ga Memory for antigen is a defining feature of adaptive immunity. Antigen-specific lymphocyte populations show an increase in number and function after antigen encounter and more rapidly re-expand upon subsequent antigen exposure. Studies of immune memory have primarily focused on effector B cells and T cells with microbial specificity, using prime-challenge models of infection. However, recent work has also identified persistently expanded populations of antigen-specific regulatory T cells that protect against aberrant immune responses. In this Review, we consider the parallels between memory effector T cells and memory regulatory T cells, along with the functional implications of regulatory memory in autoimmunity, antimicrobial host defence and maternal-fetal tolerance. In addition, we discuss emerging evidence for regulatory T cell memory in humans and key unanswered questions in this rapidly evolving field. |Female [MESH] |Histocompatibility, Maternal-Fetal/immunology [MESH] |Host-Pathogen Interactions/immunology [MESH] |Humans [MESH] |Immune Tolerance/immunology [MESH] |Immunologic Memory/*immunology [MESH] |Pregnancy [MESH] |T-Lymphocyte Subsets/immunology [MESH] |T-Lymphocytes, Regulatory/*immunology [MESH]Regulatory T cell memory (epmc).pdf DeepDyve Pubget Overpricing