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10.1126/sciadv.1500737 http://scihub22266oqcxt.onion/10.1126/sciadv.1500737 C4672759!4672759 !26665172     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26665172 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Adv 2015 ; 1 (11 ): e1500737 Nephropedia Template TP {{tp|p=26665172 |t=2015. Regulation of gene transcription by Polycomb proteins |pdf=|usr=}}{{26665172 }} gab.com Text Regulation of gene transcription by Polycomb proteins JO: Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=26665172 #FOAvip The Polycomb group (PcG) of proteins defines a subset of factors that physically associate and function to maintain the positional identity of cells from the embryo to adult stages. PcG has long been considered a paradigmatic model for epigenetic maintenance of gene transcription programs. Despite intensive research efforts to unveil the molecular mechanisms of action of PcG proteins, several fundamental questions remain unresolved: How many different PcG complexes exist in mammalian cells? How are PcG complexes targeted to specific loci? How does PcG regulate transcription? In this review, we discuss the diversity of PcG complexes in mammalian cells, examine newly identified modes of recruitment to chromatin, and highlight the latest insights into the molecular mechanisms underlying the function of PcGs in transcription regulation and three-dimensional chromatin conformation. Twit Text FOAVip Regulation of gene transcription by Polycomb proteins ????Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=26665172 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26665172 #FOAvip English Wikipedia <ref>{{Cite pmid|26665172 }}</ref> Regulation of gene transcription by Polycomb proteins #MMPMID26665172 Aranda S ; Mas G ; Di Croce L Sci Adv 2015[Dec]; 1 (11 ): e1500737 PMID26665172 show ga The Polycomb group (PcG) of proteins defines a subset of factors that physically associate and function to maintain the positional identity of cells from the embryo to adult stages. PcG has long been considered a paradigmatic model for epigenetic maintenance of gene transcription programs. Despite intensive research efforts to unveil the molecular mechanisms of action of PcG proteins, several fundamental questions remain unresolved: How many different PcG complexes exist in mammalian cells? How are PcG complexes targeted to specific loci? How does PcG regulate transcription? In this review, we discuss the diversity of PcG complexes in mammalian cells, examine newly identified modes of recruitment to chromatin, and highlight the latest insights into the molecular mechanisms underlying the function of PcGs in transcription regulation and three-dimensional chromatin conformation. äRegulation of gene transcription by Polycomb proteins (epmc).pdf DeepDyve Pubget Overpricing