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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Immunol+Res
2018 ; 2018
(ä): 1264074
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Regulation of Immune Function by Polyphenols
#MMPMID29850614
Ding S
; Jiang H
; Fang J
J Immunol Res
2018[]; 2018
(ä): 1264074
PMID29850614
show ga
Immune dysfunction is caused by various factors, including changes in relevant
immune regulators and environmental stress. Immune system imbalance leads to a
variety of diseases in humans. Nutrition may play an essential role in immunity
by interfering with proinflammatory cytokine synthesis, immune cell regulation,
and gene expression. Polyphenols, one of many categories of natural substances,
exhibit a range of biological activities. Polyphenols promote immunity to foreign
pathogens via various pathways. Different immune cells express multiple types of
polyphenol receptors that recognise and allow cellular uptake of polyphenols,
which subsequently activate signalling pathways to initiate immune responses.
Furthermore, the polyphenols curcumin and epigallocatechin gallate can induce
epigenetic changes in cells. In summary, polyphenols can be used to regulate
intestinal mucosal immune responses, allergic diseases, and antitumour immunity.