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10.5483/bmbrep.2018.51.3.012 http://scihub22266oqcxt.onion/10.5483/bmbrep.2018.51.3.012 C5882222!5882222 !29353600     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29353600 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29353600 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMB+Rep 2018 ; 51 (3 ): 151-156 Nephropedia Template TP {{tp|p=29353600 |t=2018. Regulation of Hippo signaling by actin remodeling |pdf=|usr=}}{{29353600 }} gab.com Text Regulation of Hippo signaling by actin remodeling JO: BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip The Hippo signaling pathway controls nuclear accumulation and stability of the transcriptional coregulator YAP and its paralog TAZ. The activity of Hippo-YAP signaling is influenced not only by biochemical signals, but also by cell shape and mechanical tension transmitted through cell-cell junctions and cell-matrix adhesions. Data accumulated thus far indicates that the actin cytoskeleton is a key mediator of the regulation of Hippo-YAP signaling by means of a variety of biochemical and mechanical cues. In this review, we have outlined the role of actin dynamics and actin-associated proteins in the regulation of Hippo-YAP signaling. In addition, we discuss actinmediated regulation of YAP/TAZ activity independent of the core Hippo kinases MST and LATS. Although our understanding of the link between Hippo-YAP signaling and the actin cytoskeleton is progressing rapidly, many open questions remain. [BMB Reports 2018; 51(3): 151-156]. Twit Text FOAVip Regulation of Hippo signaling by actin remodeling ????BMB Rep http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29353600 #FOAvip English Wikipedia <ref>{{Cite pmid|29353600 }}</ref> Regulation of Hippo signaling by actin remodeling #MMPMID29353600 Seo J ; Kim J BMB Rep 2018[Mar]; 51 (3 ): 151-156 PMID29353600 show ga The Hippo signaling pathway controls nuclear accumulation and stability of the transcriptional coregulator YAP and its paralog TAZ. The activity of Hippo-YAP signaling is influenced not only by biochemical signals, but also by cell shape and mechanical tension transmitted through cell-cell junctions and cell-matrix adhesions. Data accumulated thus far indicates that the actin cytoskeleton is a key mediator of the regulation of Hippo-YAP signaling by means of a variety of biochemical and mechanical cues. In this review, we have outlined the role of actin dynamics and actin-associated proteins in the regulation of Hippo-YAP signaling. In addition, we discuss actinmediated regulation of YAP/TAZ activity independent of the core Hippo kinases MST and LATS. Although our understanding of the link between Hippo-YAP signaling and the actin cytoskeleton is progressing rapidly, many open questions remain. [BMB Reports 2018; 51(3): 151-156]. |Actin Cytoskeleton/metabolism [MESH] |Actins/*metabolism [MESH] |Animals [MESH] |Hippo Signaling Pathway [MESH] |Humans [MESH] |Mechanotransduction, Cellular/genetics/physiology [MESH] |Protein Serine-Threonine Kinases/*metabolism [MESH]Regulation of Hippo signaling by actin remodeling (epmc).pdf DeepDyve Pubget Overpricing