Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28674531
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Front+Immunol
2017 ; 8
(ä): 665
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Recurrent and Sustained Viral Infections in Primary Immunodeficiencies
#MMPMID28674531
Ruffner MA
; Sullivan KE
; Henrickson SE
Front Immunol
2017[]; 8
(ä): 665
PMID28674531
show ga
Viral infections are commonplace and often innocuous. Nevertheless, within the
population of patients with primary immunodeficiencies (PIDDs), viral infections
can be the feature that drives a diagnostic evaluation or can be the most
significant morbidity for the patient. This review is focused on the viral
complications of PIDDs. It will focus on respiratory viruses, the most common
type of viral infection in the general population. Children and adults with an
increased frequency or severity of respiratory viral infections are often
referred for an immunologic evaluation. The classic teaching is to investigate
humoral function in people with recurrent sinopulmonary infections, but this is
often interpreted to mean recurrent bacterial infections. Recurrent or very
severe viral infections may also be a harbinger of a primary immunodeficiency as
well. This review will also cover persistent cutaneous viral infections, systemic
infections, central nervous system infections, and gastrointestinal infections.
In each case, the specific viral infections may drive a diagnostic evaluation
that is specific for that type of virus. This review also discusses the
management of these infections, which can become problematic in patients with
PIDDs.