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2016 ; 263
(6
): 1241-54
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Recent advances in amyotrophic lateral sclerosis
#MMPMID27025851
Riva N
; Agosta F
; Lunetta C
; Filippi M
; Quattrini A
J Neurol
2016[Jun]; 263
(6
): 1241-54
PMID27025851
show ga
ALS is a relentlessly progressive and fatal disease, with no curative therapies
available to date. Symptomatic and palliative care, provided in a
multidisciplinary context, still remains the cornerstone of ALS management.
However, our understanding of the molecular mechanisms underlying the disease has
advanced greatly over the past years, giving new hope for the development of
novel diagnostic and therapeutic approaches. Here, we have reviewed the most
recent studies that have contributed to improving both clinical management and
our understanding of ALS pathogenesis.