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2016 ; 50
(3
): 196-206
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English Wikipedia
Recent Advances in Nuclear Cardiology
#MMPMID27540423
Lee WW
Nucl Med Mol Imaging
2016[Sep]; 50
(3
): 196-206
PMID27540423
show ga
Nuclear cardiology is one of the major fields of nuclear medicine practice.
Myocardial perfusion studies using single-photon emission computed tomography
(SPECT) have played a crucial role in the management of coronary artery diseases.
Positron emission tomography (PET) has also been considered an important tool for
the assessment of myocardial viability and perfusion. However, the recent
development of computed tomography (CT)/magnetic resonance imaging (MRI)
technologies and growing concerns about the radiation exposure of patients remain
serious challenges for nuclear cardiology. In response to these challenges,
remarkable achievements and improvements are currently in progress in the field
of myocardial perfusion imaging regarding the applicable software and hardware.
Additionally, myocardial perfusion positron emission tomography (PET) is
receiving increasing attention owing to its unique capability of absolute
myocardial blood flow estimation. An F-18-labeled perfusion agent for PET is
under clinical trial with promising interim results. The applications of F-18
fluorodeoxyglucose (FDG) and F-18 sodium fluoride (NaF) to cardiovascular
diseases have revealed details on the basic pathophysiology of ischemic heart
diseases. PET/MRI seems to be particularly promising for nuclear cardiology in
the future. Restrictive diseases, such as cardiac sarcoidosis and amyloidosis,
are effectively evaluated using a variety of nuclear imaging tools. Considering
these advances, the current challenges of nuclear cardiology will become
opportunities if more collaborative efforts are devoted to this exciting field of
nuclear medicine.