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2017 ; 33
(21
): 3461-3467
Nephropedia Template TP
Sidiropoulos K
; Viteri G
; Sevilla C
; Jupe S
; Webber M
; Orlic-Milacic M
; Jassal B
; May B
; Shamovsky V
; Duenas C
; Rothfels K
; Matthews L
; Song H
; Stein L
; Haw R
; D'Eustachio P
; Ping P
; Hermjakob H
; Fabregat A
Bioinformatics
2017[Nov]; 33
(21
): 3461-3467
PMID29077811
show ga
MOTIVATION: Reactome is a free, open-source, open-data, curated and peer-reviewed
knowledge base of biomolecular pathways. Pathways are arranged in a hierarchical
structure that largely corresponds to the GO biological process hierarchy,
allowing the user to navigate from high level concepts like immune system to
detailed pathway diagrams showing biomolecular events like membrane transport or
phosphorylation. Here, we present new developments in the Reactome visualization
system that facilitate navigation through the pathway hierarchy and enable
efficient reuse of Reactome visualizations for users' own research presentations
and publications. RESULTS: For the higher levels of the hierarchy, Reactome now
provides scalable, interactive textbook-style diagrams in SVG format, which are
also freely downloadable and editable. Repeated diagram elements like
'mitochondrion' or 'receptor' are available as a library of graphic elements.
Detailed lower-level diagrams are now downloadable in editable PPTX format as
sets of interconnected objects. AVAILABILITY AND IMPLEMENTATION:
http://reactome.org. CONTACT: fabregat@ebi.ac.uk or hhe@ebi.ac.uk.