Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25296311
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25296311
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Biophys+J
2014 ; 107
(7
): 1591-600
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Raft formation in lipid bilayers coupled to curvature
#MMPMID25296311
Sadeghi S
; Müller M
; Vink RL
Biophys J
2014[Oct]; 107
(7
): 1591-600
PMID25296311
show ga
We present computer simulations of a membrane in which the local composition is
coupled to the local membrane curvature. At high temperatures (i.e., above the
temperature of macroscopic phase separation), finite-sized transient domains are
observed, reminiscent of lipid rafts. The domain size is in the range of hundred
nanometers, and set by the membrane elastic properties. These findings are in
line with the notion of the membrane as a curvature-induced microemulsion. At low
temperature, the membrane phase separates. The transition to the phase-separated
regime is continuous and belongs to the two-dimensional Ising universality class
when the coupling to curvature is weak, but becomes first-order for strong
curvature-composition coupling.