Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26673861
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Ultrason
2014 ; 14
(58
): 241-51
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Radiosynovectomy in rheumatic diseases
#MMPMID26673861
?wik?a JB
; ?bikowski P
; Kwiatkowska B
; Buscombe JR
; Sudo?-Szopi?ska I
J Ultrason
2014[Sep]; 14
(58
): 241-51
PMID26673861
show ga
Radiosynovectomy is a safe and repeatable treatment method of chronic synovitis
with synovial overgrowth and refractory chronic or acute inflammatory joint
effusion. It consist in the intraarticular administration of a radioactive
isotope in the form of a colloid causing the extinguishing of active synovitis.
The radiocolloid causes permanent irradiation of the synovium with beta ray
electron beams, which ultimately leads to its fibrosis and extinguishes the
inflammatory process destroying the joint. The main indications for
radiosynovectomy include chronic and acute arthritis in the course of systemic
diseases, intraarticular bleeding in hemorrhagic diatheses (hemophilia), selected
cases of osteoarthritis, recurrent effusions following surgery, e.g.
arthroplasty, or other iatrogenic post-surgery complications causing arthritis.
Radiosynovectomy is also performed in pigmented villonodular synovitis and
crystal synovitis. The most common method used to determine the eligibility for
radiosynovectomy is an ultrasound, which shows the location and activity of the
thickened synovium. The administration of a radiocolloid into the joint, sheath
or bursa should also be performed under the control of the ultrasound image, as
this ensures a precise location of the puncture needle and full control of the
isotope administration process. Clinical efficacy of radiosynovectomy depends on
the proper qualification of patients for the procedure. The success rate of
radiosynovectomy in common indications is 65-80%. It is confirmed by the
visualization of avascular (fibrotic) synovium in follow-up ultrasound tests. The
aim of this article is to present techniques and indications for the
radiosynovectomy treatment.