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10.3390/ijms17040560

http://scihub22266oqcxt.onion/10.3390/ijms17040560
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C4849016!4849016 !27089327
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suck abstract from ncbi


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pmid27089327
      Int+J+Mol+Sci 2016 ; 17 (4 ): 560
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  • RNase 7 in Cutaneous Defense #MMPMID27089327
  • Rademacher F ; Simanski M ; Harder J
  • Int J Mol Sci 2016[Apr]; 17 (4 ): 560 PMID27089327 show ga
  • RNase 7 belongs to the RNase A superfamily and exhibits a broad spectrum of antimicrobial activity against various microorganisms. RNase 7 is expressed in human skin, and expression in keratinocytes can be induced by cytokines and microbes. These properties suggest that RNase 7 participates in innate cutaneous defense. In this review, we provide an overview about the role of RNase 7 in cutaneous defense with focus on the molecular mechanism of the antimicrobial activity of RNase 7, the regulation of RNase 7 expression, and the role of RNase 7 in skin diseases.
  • |Animals [MESH]
  • |Anti-Infective Agents/analysis/*immunology [MESH]
  • |Bacteria/immunology [MESH]
  • |Bacterial Infections/genetics/*immunology/microbiology [MESH]
  • |Bacterial Physiological Phenomena [MESH]
  • |Gene Expression Regulation [MESH]
  • |Host-Pathogen Interactions [MESH]
  • |Humans [MESH]
  • |Immunity, Innate [MESH]
  • |Ribonucleases/analysis/genetics/*immunology [MESH]
  • |Skin Diseases/genetics/*immunology/microbiology [MESH]
  • |Skin/immunology/*microbiology/*virology [MESH]
  • |Virus Diseases/genetics/*immunology/virology [MESH]
  • |Virus Physiological Phenomena [MESH]


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