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10.1038/nrm2178

http://scihub22266oqcxt.onion/10.1038/nrm2178
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C5507177!5507177 !17473849
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suck abstract from ncbi


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pmid17473849
      Nat+Rev+Mol+Cell+Biol 2007 ; 8 (6 ): 479-90
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  • RNA-binding proteins: modular design for efficient function #MMPMID17473849
  • Lunde BM ; Moore C ; Varani G
  • Nat Rev Mol Cell Biol 2007[Jun]; 8 (6 ): 479-90 PMID17473849 show ga
  • Many RNA-binding proteins have modular structures and are composed of multiple repeats of just a few basic domains that are arranged in various ways to satisfy their diverse functional requirements. Recent studies have investigated how different modules cooperate in regulating the RNA-binding specificity and the biological activity of these proteins. They have also investigated how multiple modules cooperate with enzymatic domains to regulate the catalytic activity of enzymes that act on RNA. These studies have shown how, for many RNA-binding proteins, multiple modules define the fundamental structural unit that is responsible for biological function.
  • |*Protein Conformation [MESH]
  • |Animals [MESH]
  • |Catalytic Domain [MESH]
  • |Dimerization [MESH]
  • |Enzyme Activation [MESH]
  • |Humans [MESH]
  • |Models, Molecular [MESH]
  • |Nucleic Acid Conformation [MESH]
  • |RNA-Binding Proteins/chemistry/*genetics/*metabolism [MESH]


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