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2017 ; 25
(3
): 177-184
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Quantum dot light emitting devices for photomedical applications
#MMPMID28867926
Chen H
; He J
; Lanzafame R
; Stadler I
; Hamidi HE
; Liu H
; Celli J
; Hamblin MR
; Huang Y
; Oakley E
; Shafirstein G
; Chung HK
; Wu ST
; Dong Y
J Soc Inf Disp
2017[Mar]; 25
(3
): 177-184
PMID28867926
show ga
While OLEDs have struggled to find a niche lighting application that can fully
take advantage of their unique form factors as thin, flexible, lightweight and
uniformly large-area luminaire, photomedical researchers have been in search of
low-cost, effective illumination devices with such form factors that could
facilitate widespread clinical applications of photodynamic therapy (PDT) or
photobiomodulation (PBM). Although existing OLEDs with either fluorescent or
phosphorescent emitters cannot achieve the required high power density at the
right wavelength windows for photomedicine, the recently developed ultrabright
and efficient deep red quantum dot light emitting devices (QLEDs) can nicely fit
into this niche. Here, we report for the first time the in-vitro study to
demonstrate that this QLED-based photomedical approach could increase cell
metabolism over control systems for PBM and kill cancerous cells efficiently for
PDT. The perspective of developing wavelength-specific, flexible QLEDs for two
critical photomedical fields (wound repair and cancer treatment) will be
presented with their potential impacts summarized. The work promises to generate
flexible QLED-based light sources that could enable the widespread use and
clinical acceptance of photomedical strategies including PDT and PBM.