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10.1038/srep11598

http://scihub22266oqcxt.onion/10.1038/srep11598
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C4650600!4650600 !26111759
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suck abstract from ncbi


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pmid26111759
      Sci+Rep 2015 ; 5 (ä): 11598
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  • Quantitative analysis of the human T cell palmitome #MMPMID26111759
  • Morrison E ; Kuropka B ; Kliche S ; Brügger B ; Krause E ; Freund C
  • Sci Rep 2015[Jun]; 5 (ä): 11598 PMID26111759 show ga
  • Palmitoylation is a reversible post-translational modification used to inducibly compartmentalize proteins in cellular membranes, affecting the function of receptors and intracellular signaling proteins. The identification of protein "palmitomes" in several cell lines raises the question to what extent this modification is conserved in primary cells. Here we use primary T cells with acyl-biotin exchange and quantitative mass spectrometry to identify a pool of proteins previously unreported as palmitoylated in vivo.
  • |*Protein Processing, Post-Translational [MESH]
  • |Blotting, Western [MESH]
  • |Cells, Cultured [MESH]
  • |Chromatography, Liquid [MESH]
  • |Humans [MESH]
  • |Jurkat Cells [MESH]
  • |Lipoylation [MESH]
  • |Proteome/*metabolism [MESH]
  • |Proteomics/*methods [MESH]
  • |T-Lymphocytes/*metabolism [MESH]


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