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2015 ; 94
(1
): e352
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Qigong for hypertension: a systematic review
#MMPMID25569652
Xiong X
; Wang P
; Li X
; Zhang Y
Medicine (Baltimore)
2015[Jan]; 94
(1
): e352
PMID25569652
show ga
The purpose of this review was to evaluate the efficacy and safety of qigong for
hypertension.A systematic literature search was performed in 7 databases from
their respective inceptions until April 2014, including the Cochrane Library,
EMBASE, PubMed, Chinese Scientific Journal Database, Chinese Biomedical
Literature Database, Wanfang database, and Chinese National Knowledge
Infrastructure. Randomized controlled trials of qigong as either monotherapy or
adjunctive therapy with antihypertensive drugs versus no intervention, exercise,
or antihypertensive drugs for hypertension were identified. The risk of bias was
assessed using the tool described in Cochrane Handbook for Systematic Review of
Interventions, version 5.1.0.Twenty trials containing 2349 hypertensive patients
were included in the meta-analysis. The risk of bias was generally high. Compared
with no intervention, qigong significantly reduced systolic blood pressure (SBP)
(weighted mean difference [WMD]?=?-17.40?mm Hg, 95% confidence interval [CI]
-21.06 to -13.74, P?0.00001) and diastolic blood pressure (DBP)
(WMD?=?-10.15?mm Hg, 95% CI -13.99 to -6.30, P?0.00001). Qigong was inferior to
exercise in decreasing SBP (WMD?=?6.51?mm Hg, 95% CI 2.81 to 10.21, P?=?0.0006),
but no significant difference between the effects of qigong and exercise on DBP
(WMD?=?0.67?mm Hg, 95% CI -1.39 to 2.73, P?=?0.52) was identified. Compared with
antihypertensive drugs, qigong produced a clinically meaningful but not
statistically significant reduction in SBP (WMD?=?-7.91?mm Hg, 95% CI -16.81 to
1.00, P?=?0.08), but appeared to be more effective in lowering DBP
(WMD?=?-6.08?mm Hg, 95% CI -9.58 to -2.58, P?=?0.0007). Qigong plus
antihypertensive drugs significantly lowered both SBP (WMD?=?-11.99?mm Hg, 95% CI
-15.59 to -8.39, P?0.00001) and DBP (WMD?=?-5.28?mm Hg, 95% CI, -8.13 to -2.42,
P?=?0.0003) compared with antihypertensive drugs alone. No serious adverse events
were reported.The meta-analysis suggests that qigong is an effective therapy for
hypertension. However, more rigorously designed randomized controlled trials with
long-term follow-up focusing on hard clinical outcomes are required to confirm
the results.