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2016 ; 20
(3
): 656-61
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Pylephlebitis: a Review of 95 Cases
#MMPMID26160320
Choudhry AJ
; Baghdadi YM
; Amr MA
; Alzghari MJ
; Jenkins DH
; Zielinski MD
J Gastrointest Surg
2016[Mar]; 20
(3
): 656-61
PMID26160320
show ga
Pylephlebitis, or suppurative thrombophlebitis of the portal mesenteric venous
system occurring in the setting of abdominal inflammatory processes, is a rare
but deadly disease commonly associated with diverticulitis. We review our
institutional experience in the management of patients with this condition. A
retrospective review of medical records from 2002 to 2012 was performed. Patients
with a portal mesenteric vein thrombosis (PMVT) within 30 days of an
intra-abdominal inflammatory process were identified and evaluated. Ninety-five
patients were included. The mean patient age at presentation was 57 years (range,
24-88). The most common associated processes were pancreatitis (31 %), followed
by diverticulitis (19 %). Bacteremia was noted in 34 (44 %) patients. The most
common organism cultured was Streptococcus viridans. Antibiotic and
anticoagulation therapy was given in 86 (91 %) and 78 (82 %) patients,
respectively. Overall, we report an 11 % mortality rate. Albeit rare,
pylephlebitis most commonly was manifested in the setting of pancreatitis.
Treatment should be individualized to culture results and extent of thrombosis.
If diagnosed early and managed appropriately, a favorable outcome is possible.