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2016 ; 2016
(ä): 7494202
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Pulmonary Nocardiosis: Review of Cases and an Update
#MMPMID27445562
Shariff M
; Gunasekaran J
Can Respir J
2016[]; 2016
(ä): 7494202
PMID27445562
show ga
Nocardia, a branching, filamentous bacteria, is widely distributed in the
environment and can cause human infection in immune-compromised hosts. Inhalation
of Nocardia leads to pulmonary disease. Microbiology laboratory processed the
clinical samples from patients with respiratory infections. Smears were prepared
from the samples and were stained and cultured. Five cases were positive for
Nocardia. They were treated with the trimethoprim-sulfamethoxazole combination.
The disease was cured in three patients, and two died due to other comorbid
conditions leading to complications. Nocardiosis is encountered in parts of the
world even where it is not endemic due to increased world travel. So physicians
and laboratory staff should be aware of this and try to diagnose it. Early
detection can lead to the prompt initiation of treatment and reduced mortality in
these patients. Patients with disseminated or severe nocardiosis should be
treated with combination therapy with two or more active agents.
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