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2017 ; 76
(3
): 377-390
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Psoriasis and comorbid diseases: Epidemiology
#MMPMID28212759
Takeshita J
; Grewal S
; Langan SM
; Mehta NN
; Ogdie A
; Van Voorhees AS
; Gelfand JM
J Am Acad Dermatol
2017[Mar]; 76
(3
): 377-390
PMID28212759
show ga
Psoriasis is a common chronic inflammatory disease of the skin that is
increasingly being recognized as a systemic inflammatory disorder. Psoriatic
arthritis is a well-known comorbidity of psoriasis. A rapidly expanding body of
literature in various populations and settings supports additional associations
between psoriasis and cardiometabolic diseases, gastrointestinal diseases, kidney
disease, malignancy, infection, and mood disorders. The pathogenesis of comorbid
disease in patients with psoriasis remains unknown; however, shared inflammatory
pathways, cellular mediators, genetic susceptibility, and common risk factors are
hypothesized to be contributing elements. As additional psoriasis comorbidities
continue to emerge, education of health care providers is essential to ensuring
comprehensive medical care for patients with psoriasis.
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