Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26380057
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26380057
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 World+J+Gastrointest+Oncol
2015 ; 7
(9
): 141-7
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Proton therapy for pancreatic cancer
#MMPMID26380057
Nichols RC
; Huh S
; Li Z
; Rutenberg M
World J Gastrointest Oncol
2015[Sep]; 7
(9
): 141-7
PMID26380057
show ga
Radiotherapy is commonly offered to patients with pancreatic malignancies
although its ultimate utility is compromised since the pancreas is surrounded by
exquisitely radiosensitive normal tissues, such as the duodenum, stomach,
jejunum, liver, and kidneys. Proton radiotherapy can be used to create dose
distributions that conform to tumor targets with significant normal tissue
sparing. Because of this, protons appear to represent a superior modality for
radiotherapy delivery to patients with unresectable tumors and those receiving
postoperative radiotherapy. A particularly exciting opportunity for protons also
exists for patients with resectable and marginally resectable disease. In this
paper, we review the current literature on proton therapy for pancreatic cancer
and discuss scenarios wherein the improvement in the therapeutic index with
protons may have the potential to change the management paradigm for this
malignancy.