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2015 ; 1261
(ä): 3-20
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English Wikipedia
Protein structure annotation resources
#MMPMID25502191
Gabanyi MJ
; Berman HM
Methods Mol Biol
2015[]; 1261
(ä): 3-20
PMID25502191
show ga
A key reason three-dimensional (3-D) protein structures are annotated with
supporting or derived information is to understand the molecular basis of protein
function. To this end, protein structure annotation databases curate key facts
and observations, based on community-accepted standards, about the ~100,000 3-D
experimental protein structures to date. This review will introduce the primary
structure repositories, databases, and value-added structural annotation
databases, as well as the range of information they provide. The different levels
of annotation data (primary vs. derived vs. inferred) and how they should all be
considered accordingly will also be described.