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10.1152/ajprenal.00321.2015 http://scihub22266oqcxt.onion/10.1152/ajprenal.00321.2015 C4835926!4835926 !26719362     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26719362 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26719362 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Am+J+Physiol+Renal+Physiol 2016 ; 310 (8 ): F697-F704 Nephropedia Template TP {{tp|p=26719362 |t=2016. Protection of nitro-fatty acid against kidney diseases |pdf=|usr=}}{{26719362 }} gab.com Text Protection of nitro-fatty acid against kidney diseases JO: Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26719362 #FOAvip Nitrated derivatives of unsaturated fatty acids are endogenously formed under oxidative and nitrative stress condition and are defined as electrophilic fatty acids containing a nitro group to a carbon-carbon double bond. Among the most studied nitro derivatives of unsaturated fatty acids are nitro-oleic acid (OA-NO(2)) and nitro-linoleic acid (LNO(2)). These products exhibit novel protective actions in a variety of rodent disease models. Diverse signaling events are responsible for effects of nitrated fatty acid, including activating peroxisome proliferator-activated receptor-dependent gene expression, suppressing NF-?B-induced inflammation, inhibiting oxidative stress, and increasing both endothelial nitric oxide synthase- and Nrf2-dependent gene regulation. Nitrated fatty acids have been emerging not only as a unique class of signaling molecules produced endogenously and but also as multipotent modulators of cell signaling pathways in cardiovascular and renal diseases. In this review, we discuss biochemical properties of nitrated fatty acid and its signaling pathways in the modulation of cellular events. A major focus is to review recent knowledge of nitrated fatty acid on the treatment of kidney diseases and its therapeutic potential for inflammation and metabolic disorders, with special emphasis on acute kidney injury and diabetic kidney disease. Twit Text FOAVip Protection of nitro-fatty acid against kidney diseases ????Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26719362 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26719362 #FOAvip English Wikipedia <ref>{{Cite pmid|26719362 }}</ref> Protection of nitro-fatty acid against kidney diseases #MMPMID26719362 Wang W ; Li C ; Yang T Am J Physiol Renal Physiol 2016[Apr]; 310 (8 ): F697-F704 PMID26719362 show ga Nitrated derivatives of unsaturated fatty acids are endogenously formed under oxidative and nitrative stress condition and are defined as electrophilic fatty acids containing a nitro group to a carbon-carbon double bond. Among the most studied nitro derivatives of unsaturated fatty acids are nitro-oleic acid (OA-NO(2)) and nitro-linoleic acid (LNO(2)). These products exhibit novel protective actions in a variety of rodent disease models. Diverse signaling events are responsible for effects of nitrated fatty acid, including activating peroxisome proliferator-activated receptor-dependent gene expression, suppressing NF-?B-induced inflammation, inhibiting oxidative stress, and increasing both endothelial nitric oxide synthase- and Nrf2-dependent gene regulation. Nitrated fatty acids have been emerging not only as a unique class of signaling molecules produced endogenously and but also as multipotent modulators of cell signaling pathways in cardiovascular and renal diseases. In this review, we discuss biochemical properties of nitrated fatty acid and its signaling pathways in the modulation of cellular events. A major focus is to review recent knowledge of nitrated fatty acid on the treatment of kidney diseases and its therapeutic potential for inflammation and metabolic disorders, with special emphasis on acute kidney injury and diabetic kidney disease. |Acute Kidney Injury/metabolism/*prevention & control [MESH] |Animals [MESH] |Diabetic Nephropathies/metabolism/*prevention & control [MESH] |Fatty Acids/*metabolism [MESH] |Humans [MESH] |Nitro Compounds/*metabolism [MESH]Protection of nitro-fatty acid against kidney diseases (epmc).pdf DeepDyve Pubget Overpricing