Clin Microbiol Rev
2014[Apr]; 27
(2
): 302-45
PMID24696437
show ga
Prosthetic joint infection (PJI) is a tremendous burden for individual patients
as well as the global health care industry. While a small minority of joint
arthroplasties will become infected, appropriate recognition and management are
critical to preserve or restore adequate function and prevent excess morbidity.
In this review, we describe the reported risk factors for and clinical
manifestations of PJI. We discuss the pathogenesis of PJI and the numerous
microorganisms that can cause this devastating infection. The recently proposed
consensus definitions of PJI and approaches to accurate diagnosis are reviewed in
detail. An overview of the treatment and prevention of this challenging condition
is provided.