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2015 ; 16
(11
): 27433-49
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Prostate Cancer Stem Cells: Research Advances
#MMPMID26593898
Jaworska D
; Król W
; Szliszka E
Int J Mol Sci
2015[Nov]; 16
(11
): 27433-49
PMID26593898
show ga
Cancer stem cells have been defined as cells within a tumor that possesses the
capacity to self-renew and to cause the heterogeneous lineages of cancer cells
that comprise the tumor. Experimental evidence showed that these highly
tumorigenic cells might be responsible for initiation and progression of cancer
into invasive and metastatic disease. Eradicating prostate cancer stem cells, the
root of the problem, has been considered as a promising target in prostate cancer
treatment to improve the prognosis for patients with advanced stages of the
disease.