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2020 ; 503
(ä): 110388
Nephropedia Template TP
J Theor Biol
2020[Oct]; 503
(ä): 110388
PMID32653320
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Much work has considered the evolution of pathogens, but little is known about
how they respond to changes in host behaviour. We build a model of sublethal
disease effects where hosts are able to choose to engage in prophylactic measures
that reduce the likelihood of disease transmission. This choice is mediated by
utility costs and benefits associated with prophylaxis, and the fraction of hosts
engaged in prophylaxis is also affected by population dynamics. When prophylactic
host behaviour occurs, we find that the level of pathogen host exploitation is
reduced, by the action of selection, relative to the level that would otherwise
be predicted in the absence of prophylaxis. Our work emphasizes the significance
of the transmission-recovery trade-off faced by the pathogen and the ability of
the pathogen to influence host prophylactic behaviour.