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2014 ; 32
(26
): 2855-63
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Promise and pitfalls of heavy-particle therapy
#MMPMID25113772
Mitin T
; Zietman AL
J Clin Oncol
2014[Sep]; 32
(26
): 2855-63
PMID25113772
show ga
Proton beam therapy, the most common form of heavy-particle radiation therapy, is
not a new invention, but it has gained considerable public attention because of
the high cost of installing and operating the rapidly increasing number of
treatment centers. This article reviews the physical properties of proton beam
therapy and focuses on the up-to-date clinical evidence comparing proton beam
therapy with the more standard and widely available radiation therapy treatment
alternatives. In a cost-conscious era of health care, the hypothetical benefits
of proton beam therapy will have to be supported by demonstrable clinical gains.
Proton beam therapy represents, through its scale and its cost, a battleground
for the policy debate around managing expensive technology in modern medicine.