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10.1016/j.tibs.2014.04.006 http://scihub22266oqcxt.onion/10.1016/j.tibs.2014.04.006 C4041519!4041519 !24836995     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24836995 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Biochem+Sci 2014 ; 39 (6 ): 257-9 Nephropedia Template TP {{tp|p=24836995 |t=2014. Prokaryotic Argonautes defend genomes against invasive DNA |pdf=|usr=}}{{24836995 }} gab.com Text Prokaryotic Argonautes defend genomes against invasive DNA JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=24836995 #FOAvip Argonaute proteins are central players in small RNA-mediated silencing mechanisms such as RNA interference (RNAi), microRNA repression and piRNA-mediated transposon silencing. In eukaryotes, Argonautes bind small RNAs that guide them to RNA targets in order to regulate gene expression and repress invasive genomic elements. Although Argonaute proteins are conserved in all life forms from bacteria to eukaryotes, until now studies have focused on the biological functions of eukaryotic Argonautes. Here we highlight two recent studies that discover the functions of prokaryotic Argonautes in defence against exogenous DNA. Twit Text FOAVip Prokaryotic Argonautes defend genomes against invasive DNA ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=24836995 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24836995 #FOAvip English Wikipedia <ref>{{Cite pmid|24836995 }}</ref> Prokaryotic Argonautes defend genomes against invasive DNA #MMPMID24836995 Hur JK ; Olovnikov I ; Aravin AA Trends Biochem Sci 2014[Jun]; 39 (6 ): 257-9 PMID24836995 show ga Argonaute proteins are central players in small RNA-mediated silencing mechanisms such as RNA interference (RNAi), microRNA repression and piRNA-mediated transposon silencing. In eukaryotes, Argonautes bind small RNAs that guide them to RNA targets in order to regulate gene expression and repress invasive genomic elements. Although Argonaute proteins are conserved in all life forms from bacteria to eukaryotes, until now studies have focused on the biological functions of eukaryotic Argonautes. Here we highlight two recent studies that discover the functions of prokaryotic Argonautes in defence against exogenous DNA. |*Genome [MESH] |*RNA Interference [MESH] |Animals [MESH] |Argonaute Proteins/*physiology [MESH] |DNA/*genetics [MESH] |Humans [MESH] |Infections/etiology/*genetics [MESH]Prokaryotic Argonautes defend genomes against invasive DNA (epmc).pdf DeepDyve Pubget Overpricing