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10.1038/srep10826 http://scihub22266oqcxt.onion/10.1038/srep10826 C4455305!4455305 !26043430     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26043430 &cmd=llinks): Failed to open stream: HTTP request failed! 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Programming cancer through phase-functionalized silicon based biomaterials |pdf=|usr=}}{{26043430 }} gab.com Text Programming cancer through phase-functionalized silicon based biomaterials JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26043430 #FOAvip Applications of biomaterials in cancer therapy has been limited to drug delivery systems and markers in radiation therapy. In this article, we introduce the concept of phase-functionalization of silicon to preferentially select cancer cell populations for survival in a catalyst and additive free approach. Silicon is phase-functionalized by the interaction of ultrafast laser pulses, resulting in the formation of rare phases of SiO2 in conjunction with differing silicon crystal lattices. The degree of phase-functionalization is programmed to dictate the degree of repulsion of cancer cells. Unstable phases of silicon oxides are synthesized during phase-functionalization and remain stable at ambient conditions. This change in phase of silicon as well as formation of oxides contributes to changes in surface chemistry as well as surface energy. These material properties elicit in precise control of migration, cytoskeleton shape, direction and population. To the best of our knowledge, phase-functionalized silicon without any changes in topology or additive layers and its applications in cancer therapy has not been reported before. This unique programmable phase-functionalized silicon has the potential to change current trends in cancer research and generate focus on biomaterials as cancer repelling or potentially cancer killing surfaces. Twit Text FOAVip Programming cancer through phase-functionalized silicon based biomaterials ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26043430 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26043430 #FOAvip English Wikipedia <ref>{{Cite pmid|26043430 }}</ref> Programming cancer through phase-functionalized silicon based biomaterials #MMPMID26043430 Premnath P ; Venkatakrishnan K ; Tan B Sci Rep 2015[Jun]; 5 (ä): 10826 PMID26043430 show ga Applications of biomaterials in cancer therapy has been limited to drug delivery systems and markers in radiation therapy. In this article, we introduce the concept of phase-functionalization of silicon to preferentially select cancer cell populations for survival in a catalyst and additive free approach. Silicon is phase-functionalized by the interaction of ultrafast laser pulses, resulting in the formation of rare phases of SiO2 in conjunction with differing silicon crystal lattices. The degree of phase-functionalization is programmed to dictate the degree of repulsion of cancer cells. Unstable phases of silicon oxides are synthesized during phase-functionalization and remain stable at ambient conditions. This change in phase of silicon as well as formation of oxides contributes to changes in surface chemistry as well as surface energy. These material properties elicit in precise control of migration, cytoskeleton shape, direction and population. To the best of our knowledge, phase-functionalized silicon without any changes in topology or additive layers and its applications in cancer therapy has not been reported before. This unique programmable phase-functionalized silicon has the potential to change current trends in cancer research and generate focus on biomaterials as cancer repelling or potentially cancer killing surfaces. |Actin Cytoskeleton/metabolism [MESH] |Biocompatible Materials/*chemistry/therapeutic use [MESH] |Cell Line, Tumor [MESH] |Cell Nucleus/metabolism [MESH] |Drug Delivery Systems [MESH] |Humans [MESH] |Models, Theoretical [MESH] |Nanotechnology [MESH] |Neoplasms/metabolism/therapy [MESH] |Pseudopodia [MESH]Programming cancer through phase-functionalized silicon based biomater(epmc).pdf DeepDyve Pubget Overpricing