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2017 ; 9
(7
): e1446
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Procalcitonin: A Powerful Rescuer on Surgical Floors
#MMPMID28929031
Zil-E-Ali A
; Naqvi S
; Tariq M
Cureus
2017[Jul]; 9
(7
): e1446
PMID28929031
show ga
Necrotizing fasciitis (NF) is a rare but life-threatening medical and surgical
emergency. It is characterized by necrosis of the soft tissue leaving the
overlying tissue unaffected, which delays the diagnosis and treatment. Delay in
recognition of the severity of necrotizing fasciitis might lead to serious
morbidity and mortality. Diagnosis of NF relies on strong clinical
judgment, predictable by severe pain, erythema, and a presence of air under the
skin, but all of them are not always present. Management of NF is prompt surgical
intervention and antimicrobial therapy. The effectiveness depends on the timely
diagnosis of NF because it rapidly spreads and may cause irreversible damage.
Various investigations for necrotizing fasciitis have been proposed. However,
misdiagnosis is not infrequent and more work is needed to identify the different
presentations across the spectrum. We consider changing it to discuss the role of
procalcitonin in the diagnosis of necrotizing fasciitis.There is scarce
literature about its clinical role in necrotizing fasciitis although it has
evolved not only as a prognostic marker but also as a way of differentiating
between cellulitis and necrotizing fasciitis. It can also predict the future
consequences of septic shock.
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