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2016 ; 21
(2
): e10-4
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Primary immunodeficiency for the primary care provider
#MMPMID27095888
O'Keefe AW
; Halbrich M
; Ben-Shoshan M
; McCusker C
Paediatr Child Health
2016[Mar]; 21
(2
): e10-4
PMID27095888
show ga
Primary immunodeficiencies are a group of heterogeneous disorders resulting from
defects affecting the function of ?1 parts of the immune system. Current
estimates of the prevalence of primary immunodeficiency disease are one in 1200
patients. In Ontario, where the average general practitioner follows 1300 to 2000
patients, an estimated two patients will have primary immunodeficiency. With new
primary immunodeficiencies being described at an exponential rate, and those
previously described becoming better understood, it is challenging for health
care providers to stay up to date. Knowledge gaps delay diagnosis and treatment,
leading to increased morbidity and mortality. The present review aims to provide
the primary care provider with the tools necessary to recognize primary
immunodeficiency and assist in establishing diagnoses.