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2016 ; 9
(ä): 25-9
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Primary Sclerosing Cholangitis: Therapeutic Options and Surveillance Management
#MMPMID27330336
Kumar A
; Wheatley D
; Puttanna A
Clin Med Insights Gastroenterol
2016[]; 9
(ä): 25-9
PMID27330336
show ga
Primary sclerosing cholangitis is a chronic immune-mediated liver disease. Though
rare, it poses several clinical concerns for the managing physician. There are
currently limited therapeutic options in the management of the condition and weak
evidence base behind them. Endoscopic intervention is limited to those patients
with obstructing stricture-related disease, and even liver transplantation has a
risk of disease recurrence. Surveillance for inflammatory bowel disorders,
metabolic bone disease, and malignancy is paramount when managing such patients.
This article provides an overview of the condition with further focus on current
therapeutic options and guidance on surveillance management.