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10.1038/srep26792 http://scihub22266oqcxt.onion/10.1038/srep26792 C4886582!4886582 !27244673     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27244673 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2016 ; 6 (ä): 26792 Nephropedia Template TP {{tp|p=27244673 |t=2016. Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates |pdf=|usr=}}{{27244673 }} gab.com Text Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27244673 #FOAvip Reconstitution of total nephron segments after resection in the adult kidney has not been achieved; however, whether the neonatal kidney can maintain the capacity for neo-nephrogenesis after resection is unknown. We performed partial resection of the kidney in neonatal rats on postnatal days 1 (P1x kidney) and 4 (P4x kidney) and examined morphological changes and relevant factors. The P1x kidney bulged into the newly formed cortex from the wound edge, while nephrogenesis failure was prominent in the P4x kidney. Twenty-eight days post-resection, the glomerular number, cortex area, and collecting duct were preserved in the P1x kidney, whereas these parameters were markedly decreased in the P4x kidney. During normal development, Six2 expression and Six2+ nephron progenitor cells in the cap mesenchyme both rapidly disappear after birth. However, time course analysis for the P1x kidney showed that Six2 expression and Six2+ cells were well preserved in the tissue surrounding the resected area even 2 days after resection. In conclusion, our results indicate that kidneys in early neonate rats retain the capability for neo-nephrogenesis after resection; however, this ability is lost soon after birth, which may be attributed to a declining amount of Six2+ cells. Twit Text FOAVip Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27244673 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27244673 #FOAvip English Wikipedia <ref>{{Cite pmid|27244673 }}</ref> Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates #MMPMID27244673 Kirita Y ; Kami D ; Ishida R ; Adachi T ; Tamagaki K ; Matoba S ; Kusaba T ; Gojo S Sci Rep 2016[May]; 6 (ä): 26792 PMID27244673 show ga Reconstitution of total nephron segments after resection in the adult kidney has not been achieved; however, whether the neonatal kidney can maintain the capacity for neo-nephrogenesis after resection is unknown. We performed partial resection of the kidney in neonatal rats on postnatal days 1 (P1x kidney) and 4 (P4x kidney) and examined morphological changes and relevant factors. The P1x kidney bulged into the newly formed cortex from the wound edge, while nephrogenesis failure was prominent in the P4x kidney. Twenty-eight days post-resection, the glomerular number, cortex area, and collecting duct were preserved in the P1x kidney, whereas these parameters were markedly decreased in the P4x kidney. During normal development, Six2 expression and Six2+ nephron progenitor cells in the cap mesenchyme both rapidly disappear after birth. However, time course analysis for the P1x kidney showed that Six2 expression and Six2+ cells were well preserved in the tissue surrounding the resected area even 2 days after resection. In conclusion, our results indicate that kidneys in early neonate rats retain the capability for neo-nephrogenesis after resection; however, this ability is lost soon after birth, which may be attributed to a declining amount of Six2+ cells. |*Nephrectomy [MESH] |*Regeneration [MESH] |Animals [MESH] |Animals, Newborn [MESH] |Apoptosis [MESH] |Cell Proliferation [MESH] |Gene Expression [MESH] |Nephrons/growth & development/metabolism/*physiology/surgery [MESH]Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonate(epmc).pdf DeepDyve Pubget Overpricing