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10.18632/oncotarget.17975 http://scihub22266oqcxt.onion/10.18632/oncotarget.17975 C5584253!5584253 !28881652     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28881652 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Oncotarget 2017 ; 8 (31 ): 51345-51354 Nephropedia Template TP {{tp|p=28881652 |t=2017. Predictors of acute kidney injury after paraquat intoxication |pdf=|usr=}}{{28881652 }} gab.com Text Predictors of acute kidney injury after paraquat intoxication JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28881652 #FOAvip Paraquat intoxication is characterized by multi-organ failure, causing substantial mortality and morbidity. Many paraquat patients experience acute kidney injury (AKI), sometimes requiring hemodialysis. We observed 222 paraquat-intoxicated patients between 2000 and 2012, and divided them into AKI (n = 103) and non-AKI (n = 119) groups. The mortality rate was higher for AKI than non-AKI patients (70.1% vs. 40.0%, P < 0.001). Patients with AKI had a longer time to hospital arrival (P = 0.003), lower PaO(2) (P = 0.006) and higher alveolar-arterial O(2) difference (P < 0.001) 48 h after admission, higher sequential organ failure assessment 48-h score (P < 0.001), higher severity index of paraquat poisoning (SIPP) score (P = 0.016), lower PaCO(2) at admission (P = 0.031), higher PaO(2) at admission (P = 0.015), lower nadir PaCO(2) (P = 0.001) and lower nadir HCO(3) (P = 0.004) than non-AKI patients. Multivariate logistic regression indicated that acute hepatitis (P < 0.001), a longer time to hospital arrival (P < 0.001), higher SIPP score (P = 0.026) and higher PaO(2) at admission (P = 0.014) were predictors of AKI. The area under the receiver operating characteristic curve confirmed that an Acute Kidney Injury Network 48-hour score ? 2 predicted AKI necessitating hemodialysis with a sensitivity of 0.6 and specificity of 0.832. AKI is common (46.4%) following paraquat ingestion, and acute hepatitis, the time to hospital arrival, SIPP score and PaO(2) at admission were powerful predictors of AKI. Larger studies with longer follow-up durations are warranted. Twit Text FOAVip Predictors of acute kidney injury after paraquat intoxication ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28881652 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28881652 #FOAvip English Wikipedia <ref>{{Cite pmid|28881652 }}</ref> Predictors of acute kidney injury after paraquat intoxication #MMPMID28881652 Weng CH ; Chen HH ; Hu CC ; Huang WH ; Hsu CW ; Fu JF ; Lin WR ; Wang IK ; Yen TH Oncotarget 2017[Aug]; 8 (31 ): 51345-51354 PMID28881652 show ga Paraquat intoxication is characterized by multi-organ failure, causing substantial mortality and morbidity. Many paraquat patients experience acute kidney injury (AKI), sometimes requiring hemodialysis. We observed 222 paraquat-intoxicated patients between 2000 and 2012, and divided them into AKI (n = 103) and non-AKI (n = 119) groups. The mortality rate was higher for AKI than non-AKI patients (70.1% vs. 40.0%, P < 0.001). Patients with AKI had a longer time to hospital arrival (P = 0.003), lower PaO(2) (P = 0.006) and higher alveolar-arterial O(2) difference (P < 0.001) 48 h after admission, higher sequential organ failure assessment 48-h score (P < 0.001), higher severity index of paraquat poisoning (SIPP) score (P = 0.016), lower PaCO(2) at admission (P = 0.031), higher PaO(2) at admission (P = 0.015), lower nadir PaCO(2) (P = 0.001) and lower nadir HCO(3) (P = 0.004) than non-AKI patients. Multivariate logistic regression indicated that acute hepatitis (P < 0.001), a longer time to hospital arrival (P < 0.001), higher SIPP score (P = 0.026) and higher PaO(2) at admission (P = 0.014) were predictors of AKI. The area under the receiver operating characteristic curve confirmed that an Acute Kidney Injury Network 48-hour score ? 2 predicted AKI necessitating hemodialysis with a sensitivity of 0.6 and specificity of 0.832. AKI is common (46.4%) following paraquat ingestion, and acute hepatitis, the time to hospital arrival, SIPP score and PaO(2) at admission were powerful predictors of AKI. Larger studies with longer follow-up durations are warranted. ?Predictors of acute kidney injury after paraquat intoxication (epmc).pdf DeepDyve Pubget Overpricing