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10.4103/1008-682X.155536

http://scihub22266oqcxt.onion/10.4103/1008-682X.155536
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C4577583!4577583 !26067871
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suck abstract from ncbi

pmid26067871
      Asian+J+Androl 2015 ; 17 (5 ): 742-8
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  • Posttesticular sperm maturation, infertility, and hypercholesterolemia #MMPMID26067871
  • Whitfield M ; Pollet-Villard X ; Levy R ; Drevet JR ; Saez F
  • Asian J Androl 2015[Sep]; 17 (5 ): 742-8 PMID26067871 show ga
  • Cholesterol is a key molecule in the mammalian physiology of especial particular importance for the reproductive system as it is the common precursor for steroid hormone synthesis. Cholesterol is also a recognized modulator of sperm functions, not only at the level of gametogenesis. Cholesterol homeostasis regulation is crucial for posttesticular sperm maturation, and imbalanced cholesterol levels may particularly affect these posttesticular events. Metabolic lipid disorders (dyslipidemia) affect male fertility but are most of the time studied from the angle of endocrine/testicular consequences. This review will focus on the deleterious effects of a particular dyslipidemia, i.e., hypercholesterolemia, on posttesticular maturation of mammalian spermatozoa.
  • |Animals [MESH]
  • |Cholesterol/metabolism [MESH]
  • |Epididymis/*metabolism [MESH]
  • |Humans [MESH]
  • |Hypercholesterolemia/*metabolism [MESH]
  • |Infertility, Male/*metabolism [MESH]
  • |Male [MESH]
  • |Sperm Maturation/*physiology [MESH]
  • |Sperm Motility/physiology [MESH]
  • |Spermatozoa/*metabolism [MESH]


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