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2017 ; 5
(2
): 148-156
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Portal vein thrombosis in patients with cirrhosis
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von Köckritz L
; De Gottardi A
; Trebicka J
; Praktiknjo M
Gastroenterol Rep (Oxf)
2017[May]; 5
(2
): 148-156
PMID28533912
show ga
Portal vein thrombosis (PVT) is frequent in patients with liver cirrhosis and
possible severe complications such as mesenteric ischemia are rare, but can be
life-threatening. However, different aspects of clinical relevance, diagnosis and
management of PVT are still areas of uncertainty and investigation in
international guidelines. In this article, we elaborate on PVT classification,
geographical differences in clinical presentation and standards of diagnosis, and
briefly on the current pathophysiological understanding and risk factors. This
review considers and highlights the pitfalls of the various treatment approaches
and prophylactic treatments. Finally, we review the controversial issue of
clinical impact of PVT on prognosis, especially considering liver transplantation
and future perspectives.