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2015 ; 5
(3
): 1265-80
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Platelets and Their Interactions with Other Immune Cells
#MMPMID26140718
Lam FW
; Vijayan KV
; Rumbaut RE
Compr Physiol
2015[Jul]; 5
(3
): 1265-80
PMID26140718
show ga
Platelets are anucleate blood cells, long known to be critically involved in
hemostasis and thrombosis. In addition to their role in blood clots, increasing
evidence reveals significant roles for platelets in inflammation and immunity.
However, the notion that platelets represent immune cells is not broadly
recognized in the field of Physiology. This article reviews the role of platelets
in inflammation and immune responses, and highlights their interactions with
other immune cells, including examples of major functional consequences of these
interactions.