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10.3390/ijms18102200 http://scihub22266oqcxt.onion/10.3390/ijms18102200 C5666881!5666881 !29053592     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29053592 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Mol+Sci 2017 ; 18 (10 ): ä Nephropedia Template TP {{tp|p=29053592 |t=2017. Platelets and Multi-Organ Failure in Sepsis |pdf=|usr=}}{{29053592 }} gab.com Text Platelets and Multi-Organ Failure in Sepsis JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29053592 #FOAvip Platelets have received increasing attention for their role in the pathophysiology of infectious disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known biomarker for disease severity and more recently authors have focused their attention on the active role of platelets in the pathogenesis of multi-organ failure. Septic shock is characterised by a dysregulated inflammatory response, which can impair the microcirculation and lead to organ injury. Being at the crossroads between the immune system, clotting cascade, and endothelial cells, platelets seem to be an appealing central mediator and possible therapeutic target in sepsis. This review focuses on the pathogenic role of platelets in septic organ dysfunction in humans and animal models. Twit Text FOAVip Platelets and Multi-Organ Failure in Sepsis ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=29053592 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29053592 #FOAvip English Wikipedia <ref>{{Cite pmid|29053592 }}</ref> Platelets and Multi-Organ Failure in Sepsis #MMPMID29053592 Greco E ; Lupia E ; Bosco O ; Vizio B ; Montrucchio G Int J Mol Sci 2017[Oct]; 18 (10 ): ä PMID29053592 show ga Platelets have received increasing attention for their role in the pathophysiology of infectious disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known biomarker for disease severity and more recently authors have focused their attention on the active role of platelets in the pathogenesis of multi-organ failure. Septic shock is characterised by a dysregulated inflammatory response, which can impair the microcirculation and lead to organ injury. Being at the crossroads between the immune system, clotting cascade, and endothelial cells, platelets seem to be an appealing central mediator and possible therapeutic target in sepsis. This review focuses on the pathogenic role of platelets in septic organ dysfunction in humans and animal models. |Animals [MESH] |Biomarkers/blood [MESH] |Blood Platelets/*metabolism [MESH] |Humans [MESH] |Multiple Organ Failure/*blood/immunology [MESH] |Platelet Activation [MESH] |Sepsis/blood/*complications/immunology [MESH]Platelets and Multi-Organ Failure in Sepsis (epmc).pdf DeepDyve Pubget Overpricing