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10.1007/978-3-642-29423-5_3 http://scihub22266oqcxt.onion/10.1007/978-3-642-29423-5_3 C4785017!4785017 !22918727     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\22918727 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Handb+Exp+Pharmacol 2012 ; ä (210 ): 59-85 Nephropedia Template TP {{tp|p=22918727 |t=2012. Platelet signaling |pdf=|usr=}}{{22918727 }} gab.com Text Platelet signaling JO: Handb Exp Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=22918727 #FOAvip This chapter summarizes current ideas about the intracellular signaling that drives platelet responses to vascular injury. After a brief overview of platelet activation intended to place the signaling pathways into context, the first section considers the early events of platelet activation leading up to integrin activation and platelet aggregation. The focus is on the G protein-mediated events utilized by agonists such as thrombin and ADP, and the tyrosine kinase-based signaling triggered by collagen. The second section considers the events that occur after integrin engagement, some of which are dependent on close physical contact between platelets. A third section addresses the regulatory events that help to avoid unprovoked or excessive platelet activation, after which the final section briefly considers individual variations in platelet reactivity and the role of platelet signaling in the innate immune response and embryonic development. Twit Text FOAVip Platelet signaling ????Handb Exp Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=22918727 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=22918727 #FOAvip English Wikipedia <ref>{{Cite pmid|22918727 }}</ref> Platelet signaling #MMPMID22918727 Stalker TJ ; Newman DK ; Ma P ; Wannemacher KM ; Brass LF Handb Exp Pharmacol 2012[]; ä (210 ): 59-85 PMID22918727 show ga This chapter summarizes current ideas about the intracellular signaling that drives platelet responses to vascular injury. After a brief overview of platelet activation intended to place the signaling pathways into context, the first section considers the early events of platelet activation leading up to integrin activation and platelet aggregation. The focus is on the G protein-mediated events utilized by agonists such as thrombin and ADP, and the tyrosine kinase-based signaling triggered by collagen. The second section considers the events that occur after integrin engagement, some of which are dependent on close physical contact between platelets. A third section addresses the regulatory events that help to avoid unprovoked or excessive platelet activation, after which the final section briefly considers individual variations in platelet reactivity and the role of platelet signaling in the innate immune response and embryonic development. |Animals [MESH] |Blood Platelets/*physiology [MESH] |Calcium/metabolism [MESH] |GTP-Binding Proteins/physiology [MESH] |Humans [MESH] |Platelet Activation/drug effects [MESH] |Platelet Adhesiveness [MESH]Platelet signaling (epmc).pdf DeepDyve Pubget Overpricing